apalutamide will decrease the level or impact of diazepam by affecting hepatic enzyme CYP2C19 metabolism. Stay away from or Use Alternate Drug. Coadministration of apalutamide, a robust CYP2C19 inducer, with prescription drugs which are CYP2C19 substrates may end up in reduced publicity to those drugs.diazepam raises levels of lomitapide by affecti

tecovirimat will increase the amount or influence of diazepam by impacting hepatic enzyme CYP2C19 metabolism. Use Caution/Monitor. Tecovirimat is actually a weak inhibitor of CYP2C8 and CYP2C19. Keep track of for adverse results if coadministered with sensitive substrates of such enzymes.Reserve concomitant prescribing of such medications in suffer